Eldepryl use as Parkinson’s Treatment
Parkinson’s disease is a nervous system disorder characterized by a decrease in the levels of a chemical known as dopamine found in the brain. This causes movement problems which can affect a person’s way of life adversely. The only way to alleviate these symptoms is by Parkinson’s treatment geared towards increasing the levels of dopamine in the body. One such medication used to achieve this effect is Eldepryl. This is usually used together with other medications like levodopa and carbidopa though it may be prescribed for use on its own.
Eldepryl contains Selegiline hydrochloride as the active ingredient which is a selective MAO-B inhibitor. MAO-B is responsible for the metabolism or break down of dopamine and phenylethylamine. When taken, Selegiline acts to stop the action of this MAO-B causing dopamine to accumulate enhancing the reversal of Parkinson’s disease symptoms. Though the therapeutic effect of Selegiline on its own are limited, it is useful when used together with other anti-parkinson’s disease drugs and reduces their side effects. Levodopa which is the most commonly used therapeutic drug for Parkinson’s disease causes motor complications when taken in high doses. When taken together with Eldepryl however, the dosage can be reduced hence reducing the occurrence of these side effects. Eldepryl can also help delay the need to start using levodopa by up to a year.
Eldepryl is strictly a prescription-only drug which should not be taken without a recommendation by a qualified physician. Many physicians will recommend a starting dose of 5mg per day which is later on increased to 10mg. The medicine comes in the form of a tablet which is taken orally with water once a day. For best results, it should be taken at the same time every day. It is advisable not to eat or drink anything 5 minutes before or after taking the tablet. If you forget to take the tablet in time, take it as soon as you remember but if it is near the time for the next dose, skip it and continue taking the drugs as usual.
Just like any other drug, Eldepryl has several side effects. These differ from one person to another and while a person may experience several of them, another person may not experience any. They include sore mouth which is the most common and lesser common ones like stomach upsets, headaches and light-headedness, constipation, back pain, diarrhea, tiredness and nausea. Others which if experienced a doctor needs to be notified immediately include confusion, depression, blocked nose and uncontrolled muscle movement. An overdose in Selegiline can have adverse effects including a sudden decrease in blood pressure and must be reported immediately.